Journal
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
Volume 26, Issue 9, Pages 1013-1032Publisher
MOSBY-ELSEVIER
DOI: 10.1016/j.echo.2013.07.005
Keywords
Radiotherapy; Echocardiography; Cardiac magnetic resonance; Nuclear cardiology; Cardiac computed tomography; Heart disease
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Cardiac toxicity is one of themost concerning side effects of anti-cancer therapy. The gain in life expectancy obtained with anti-cancer therapy can be compromised by increased morbidity and mortality associated with its cardiac complications. While radiosensitivity of the heart was initially recognized only in the early 1970s, the heart is regarded in the current era as one of themost critical dose-limiting organs in radiotherapy. Several clinical studies have identified adverse clinical consequences of radiation-induced heart disease (RIHD) on the outcome of long-term cancer survivors. A comprehensive review of potential cardiac complications related to radiotherapy is warranted. An evidence-based review of several imaging approaches used to detect, evaluate, and monitor RIHDis discussed. Recommendations for the early identification andmonitoring of cardiovascular complications of radiotherapy by cardiac imaging are also proposed.
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