Hyposalivation, xerostomia and the complete denture - A systematic review

Background. To determine the treatment effects of hyposalivation on denture retention, the authors conducted a systematic review of the literature. Types of Studies Reviewed. The authors reviewed clinical investigations that assessed the treatment effects of hyposalivation on denture retention. They searched six electronic databases for works from 1950 to the second week of September 2007 by using the key words denture, hyposalivation, xerostomia, dry mouth, elderly and aged. They limited the citation search to articles written in English and describing studies that involved human subjects. Results. The authors identified 11 articles in the search; none was a report of a randomized controlled clinical trial. Clinical Implications. The few clinical research studies published on the topic of hyposalivation and denture retention represent a low level of evidence for establishing clinical practice guidelines. The authors found that they could make no conclusions regarding the treatment effects of hyposalivation on denture retention. The article provides a literature review regarding the etiologies and clinical presentation of salivary disorders and xerostomia in elderly people, the role of saliva in denture retention, the effect of dry mouth on denture use and the treatment of dry mouth problems in denture wearers. Prospective clinical trials are needed to establish a framework for evidence-based treatment of denture-wearing patients experiencing dry mouth.