Journal
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Volume 60, Issue 6, Pages 517-520Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jacc.2012.03.058
Keywords
coronary heart disease; high-density lipoprotein cholesterol; high-density lipoprotein particles; lipids; lipoproteins
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Limitations in our ability to predict cardiovascular risk have fueled efforts to identify novel risk markers and to refine the measurement of traditional risk factors, such as low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C). Standard assays to evaluate LDL-C and HDL-C quantify the cholesterol content within the respective lipoprotein fraction. However, both LDL and HDL particles vary in their content of cholesterol, and thus determining the concentration of lipoprotein
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