4.8 Article

Silyl Phosphorus and Nitrogen Donor Chelates for Homogeneous Ortho Borylation Catalysis

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 136, Issue 41, Pages 14345-14348

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja506229s

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Funding

  1. NIH [GM63188]
  2. NSF [GOALI-1012883]
  3. ACS Green Chemistry Institute Pharmaceutical Roundtable
  4. Direct For Mathematical & Physical Scien
  5. Division Of Chemistry [1012883] Funding Source: National Science Foundation

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Ir catalysts supported by bidentate silyl ligands that contain P- or N-donors are shown to effect ortho borylations for a range of substituted aromatics. The substrate scope is broad, and the modular ligand synthesis allows for flexible catalyst design.

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