Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 136, Issue 33, Pages 11590-11593Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja507704b
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Funding
- Shanghai Institute of Organic Chemistry
- Chinese Academy of Sciences
- CAS/SAFEA
- Recruitment Program of Global Experts
- Scripps Research Institute
- NSF under the CCI Center for Selective C-H Functionalization [CHE-1205646]
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Cu(II)-promoted ortho alkynylation of arenes and heteroarenes with terminal alkynes has been developed to prepare aryl alkynes. A variety of arenes and terminal alkynes bearing different substituents are compatible with this reaction, thus providing an alternative disconnection to Sonogashira coupling.
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