4.8 Article

Iridium-Catalyzed Annulation of Salicylimines with 1,3-Dienes

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 136, Issue 26, Pages 9284-9287

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja504990a

Keywords

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Funding

  1. MEXT, Japan
  2. JSPS
  3. Grants-in-Aid for Scientific Research [24550117, 25105730, 14J01457] Funding Source: KAKEN

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Iridium-catalyzed annulation of salicylimines with 1,3-dienes gave high yields of the corresponding 4-aminochromanes with high stereoselectivity. The use of a chiral diene ligand enabled the asymmetric reaction to give 4-aminochromanes with high enantioselectivity.

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