4.8 Article

Ligand-Controlled Palladium-Catalyzed Regiodivergent Suzuki-Miyaura Cross-Coupling of Allylboronates and Aryl Halides

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 135, Issue 29, Pages 10642-10645

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja405950c

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Funding

  1. National Institutes of Health [GM46059]

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An orthogonal set of catalyst systems has been developed for the Suzuki-Miyaura coupling of 3,3-disubstituted and 3-monosubstituted allylboronates with (hetero)aryl halides. These methods allow for the highly selective preparation of either the alpha- or the gamma-isomeric coupling product.

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