4.8 Article

Highly Enantioselective Rhodium-Catalyzed [2+2+2] Cycloaddition of Diynes to Sulfonimines

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 135, Issue 12, Pages 4576-4579

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja309301n

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Funding

  1. Universite Pierre et Marie Curie-Paris 6
  2. CNRS
  3. IUF
  4. Servier Corporation

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A new asymmetric [2+2+2] cycloaddition of diynes to sulfonimines under rhodium catalysis that provides the corresponding enantioenriched 1,2-dihydropyridines in good yields is described.

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