Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 134, Issue 30, Pages 12462-12465Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja305840g
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Funding
- National Institutes of Health [GM46059, 1S10RR13886-01]
- National Science Foundation [CHE 9808061, DBI 9729592]
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A mild, versatile, and convenient method for the efficient oxytrifluoromethylation of unactivated alkenes based on a copper-catalyzed coddative difunctionalization strategy has been developed. This methodology provides access to a variety of classes of synthetically useful CF3-containing building blocks from simple starting materials.
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