Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 134, Issue 41, Pages 16941-16943Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja307277w
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Funding
- National Institutes of Health [GM28663]
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A concise total synthesis of (+/-)-communesin F has been completed in 15 linear steps from 4-bromotryptophol in an overall yield of 6.7%. A key step features the cycloaddition of indol-2-one with 3-(2-azidoethyl)-4-bromoindole and facilitates the rapid construction of the lower aminal-containing tetracyclic core of the natural product.
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