4.8 Article

Liposome-Gold Nanorod Hybrids for High-Resolution Visualization Deep in Tissues

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 134, Issue 32, Pages 13256-13258

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja304499q

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Funding

  1. Andalusian Initiative for Advanced Therapies promoted by the Regional Government of Andalusia, Spain
  2. ERC Advanced Investigator Award
  3. German Ministry of Education (BMBF) Innovation in Medicine Award

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The design of liposome-nanoparticle hybrids offers a rich toolbox for the fabrication of multifunctional modalities. A self-assembled liposome-gold nanorod hybrid vesicular system that consists of lipid-bilayer-associated gold nanorods designed to allow deep tissue detection, therapy, and monitoring in living animals using multispectral optoacoustic tomography has been fabricated and characterized in vitro and in vivo.

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