Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 134, Issue 45, Pages 18570-18572Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja309325e
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Funding
- Scripps Research Institute
- National Institutes of Health (NIGMS) [1 R01 GM084019-02]
- Eli Lilly
- Bristol-Myers Squibb
- Agency for Science, Technology and Research (A*STAR) Singapore
- Astellas Pharma Inc.
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Pd(II) insertion into beta-methylene C(sp(3))-H bonds was enabled by a mutually repulsive and electron-rich quinoline ligand. Ligand tuning led to the development or a method that allows for installation of an aryl,, group On a range of acyclic and cyclic amides containing beta-methylene C(sp(3))-H bonds.
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