4.8 Article

Gold-Catalyzed Cycloisomerization of 1,7-Diyne Benzoates to Indeno[1,2-c]azepines and Azabicyclo[4.2.0]octa-1(8),5-dines

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 134, Issue 26, Pages 10811-10814

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja304964s

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Funding

  1. University Research Committee Grant from Nanyang Technological University [RG55/06]
  2. Science and Engineering Research Council Grant from A*STAR, Singapore [092 101 0053]

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A synthetic method that relies on Au(I)-catalyzed cycloisomerization reactions of 1,7-diyne benzoates to prepare indeno[1,2-c]azepines and azabicyclo[4.2.0]octa-1(8),5-dines is described.

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