Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 134, Issue 30, Pages 12466-12469Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja305660a
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Funding
- Novartis International AG
- National Science Foundation [CHE-9808061, DBI-9729592]
- National Institutes of Health [1S10RR13886-01]
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Anilines and ethyl vinyl ether can be used as precursors for a process that is the synthetic equivalent of the alpha-arylation of acetaldehyde enolate. The reaction manifests a high level of functional group compatibility, allowing the ready preparation of a number of synthetically valuable compounds.
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