4.8 Article

Activation of H2O2 by Chiral Confined Bronsted Acids: A Highly Enantioselective Catalytic Sulfoxidation

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 134, Issue 26, Pages 10765-10768

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja3035637

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Funding

  1. European Research Council

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Confined chiral Bronsted acids are shown to catalyze asymmetric oxidations of sulfides to sulfoxides with hydrogen peroxide. The wide generality and high enantioselectivity of the developed method compare even to the best metal-based systems and suggest utility in other asymmetric oxidations.

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