Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 134, Issue 42, Pages 17474-17477Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja308742x
Keywords
-
Categories
Funding
- Molecular Activation Directed toward Straightforward Synthesis, MEXT, Japan
- Global COE program Practical Chemical Wisdom, Waseda University, Japan
Ask authors/readers for more resources
A cationic iridium-catalyzed C2-alkylation of N-substituted indole derivatives with various alkenes has been developed, which selectively gives linear or branched 2-alkylindoles in high to excellent selectivity. This protocol relies on the use of the carbonyl group on the nitrogen atom of indole as a directing group: a linear product was predominant when an acetyl group was used as a directing group, and a branched product was predominant with a benzoyl group.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available