4.8 Article

Direct Stereospecific Amination of Alkyl and Aryl Pinacol Boronates

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 134, Issue 40, Pages 16449-16451

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja305448w

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Funding

  1. NIH [GM-59471]
  2. LaMattina Fellowship

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The direct amination of alkyl and aryl pinacol boronates is accomplished with lithiated methoxyamine. This reaction directly provides aliphatic and aromatic amines, stereospecifically, and without preactivation of the boronate substrate.

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