Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 134, Issue 29, Pages 11948-11951Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja305259n
Keywords
-
Categories
Funding
- The Scripps Research Institute
- U.S. NSF [CHE-1011898]
- Novartis
- China Scholarship Council
- National Natural Science Foundation of China [21002070]
- Direct For Mathematical & Physical Scien
- Division Of Chemistry [1011898] Funding Source: National Science Foundation
Ask authors/readers for more resources
A Pd(II)-catalyzed trifluoromethylation of ortho C-H bonds with an array of N-arylbenzamides derived from benzoic acids is reported. N-Methylformamide has been identified as a crucial promoter of C-CF3 bond formation from the Pd center. X-ray characterization of the C-H insertion intermediate has revealed a rare coordination mode of acidic amides as directing groups and the origin of their capacity in directing C-H activation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available