Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 133, Issue 7, Pages 2100-2103Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja110713k
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Funding
- National Science Foundation [CHE-0911192]
- Celgene Drug Discovery Fellowship
- Division Of Chemistry
- Direct For Mathematical & Physical Scien [0911192] Funding Source: National Science Foundation
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Aminobenzaldehydes react with indoles in an unprecedented cascade reaction. This acid-catalyzed redox-neutral annulation proceeds via a condensation/1,5-hydride shift/ring-closure sequence. Polycyclic azepinoindoles and related compounds are obtained in a single step with good to excellent yields.
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