Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 133, Issue 33, Pages 12914-12917Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja203138q
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Funding
- National Basic Research Program of China (973 program) [2010CB833300]
- Chinese Academy of Sciences
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This paper describes an effective chiral base-catalyzed biomimetic transamination of a-keto esters using simple benzyl amines. A wide variety of a.-amino esters containing various functional groups can be synthesized in high enantioselectivity and reasonable yield.
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