Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 134, Issue 2, Pages 754-757Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja207784t
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Water-soluble metalla-cages were used to deliver hydrophobic porphin molecules to cancer cells. After internalization, the photosensitizer was photoactivated, significantly increasing the cytotoxicity in cells. During the transport, the photosensitizer remains non-reactive to light, offering a new strategy to tackle overall photosensitization, a limitation often encountered in photodynamic therapy.
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