4.8 Article

1,7-Palladium Migration via C-H Activation, Followed by Intramolecular Amination: Regioselective Synthesis of Benzotriazoles

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 133, Issue 18, Pages 6868-6870

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja2007438

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Funding

  1. National Natural Science Foundation of China [J20091112]
  2. Fundamental Research Funds for the Central Universities [2010QNA3011]

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A novel 1,7-palladium migration-cyclization-dealkylation sequence for the regioselective synthesis of benzotriazoles has been developed. These reactions proceed in excellent yields with high regioselectivities. The mechanism of the reaction has also been investigated.

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