4.8 Article

Gold-Catalyzed Tandem 1,3-Migration/[2+2] Cycloaddition of 1,7-Enyne Benzoates to Azabicyclo[4.2.0]oct-5-enes

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 133, Issue 39, Pages 15248-15251

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja2052304

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Funding

  1. University Research Committee from Nanyang Technological University [RG55/06]
  2. Science and Engineering Research Council from A*STAR, Singapore [092 101 0053]

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A synthetic method that relies on gold(I)-catalyzed tandem l,3-migration/[2 + 2] cycloaddition of 1,7-enyne benzoates to prepare azabicyclo [4.2.0] oct-5-enes is described.

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