Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 133, Issue 14, Pages 5178-5181Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja111173c
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Funding
- NSF
- NRSA
- Searle Scholar Award
- Burroughs Wellcome Fund Career Award in the Biomedical Sciences
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The molecular mechanisms that lead to the generation of adipose tissue (adipogenesis) are of basic and biomedical interest. Cellular models of adipogenesis have proven extremely valuable in defining biomolecules-primarily genes and proteins-that regulate adipogenesis. Here, the analysis of differentiating adipocytes using an untargeted metabolomics approach led to the discovery of the monoalkylglycerol ethers as a natural class of adipocyte differentiation factors.
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