4.8 Article

Graphene-Based SELDI Probe with Ultrahigh Extraction and Sensitivity for DNA Oligomer

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 132, Issue 32, Pages 10976-10977

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja104017y

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Funding

  1. NRF-CRP [R-143-000-360-281]

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We demonstrate that graphene can be used as an ultrahigh efficiency preconcentration and detection platform for ssDNA. DNA-adsorbed graphene can be used directly for Surface Enhanced Laser Desorption Ionization-Time of Flight-Mass Spectrometry (SELDI-TOF-MS). The rapid enrichment of biomolecules and direct, label-free detection are potentially useful for analysis in proteomics and genomics.

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