4.8 Article

Carbon-Carbon Bond Activation by 1,1-Carboboration of Internal Alkynes

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 132, Issue 39, Pages 13594-13595

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja106365j

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Funding

  1. Deutsche Forschungsgemeinschaft
  2. Fonds der Chemischen Industrie
  3. Alexander von Humboldt Foundation

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Internal alkynes undergo 1,1-carboboration reactions upon treatment with boranes RB(C(6)F(5))(2) (R = C(6)F(5), CH(3)) to yield trisubstituted alkenylboranes. These products can be used as substrates in Pd-catalyzed cross-coupling reactions.

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