Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 132, Issue 31, Pages 10628-10629Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja101387b
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Funding
- The Anderson Cancer Center
- The Rockefeller University
- Irma T. Hirschl/Monique Weill-Caulier Trust
- Ellison Medical Foundation
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Lipoproteins are a largely uncharacterized class of proteins in bacteria. In this study, metabolic labeling of bacteria with fatty acid chemical reporters allowed rapid profiling of lipid-modified proteins. We identified many candidate lipoproteins in Escherichia coli and detected a novel modification on YjgF. This chemical approach should facilitate future characterization of lipoproteins.
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