Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 132, Issue 37, Pages 12823-12825Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja1053913
Keywords
-
Categories
Funding
- UNC Chapel Hill
Ask authors/readers for more resources
A palladium-catalyzed carbonylative Heck-type cyclization of alkyl halides is described. Treatment of a range of primary and secondary alkyl iodides with catalytic palladium(0) under CO pressure forms a variety of synthetically versatile enone products. The reactivity described represents a rare example of a palladium-catalyzed Heck-type cyclization involving unactivated alkyl halides with beta-hydrogens. Alkene substitution is well tolerated, and mono- and bicyclic carbocycles may be easily accessed.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available