4.8 Article

Palladium-Catalyzed Conversion of Aryl and Vinyl Triflates to Bromides and Chlorides

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 132, Issue 40, Pages 14076-14078

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja107481a

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Funding

  1. National Institutes of Health [GM46059]

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The palladium-catalyzed conversion of aryl and vinyl triflates to aryl and vinyl halides (bromides and chlorides) has been developed using dialkylbiaryl phosphine ligands. A variety of aryl, heteroaryl, and vinyl halides can be prepared via this method in good to excellent yields.

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