Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 132, Issue 50, Pages 17652-17654Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja108073k
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Funding
- National Natural Science Foundation of China [20625205, 20772034, 20932002]
- National Basic Research Program of China (973 Program) [2011CB808600]
- Ministry of Education of China [20090172110014]
- Guangdong Natural Science Foundation [10351064101000000]
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A new copper-catalyzed oxidative [3 + 2] cycloaddition of alkenes with anhydrides using oxygen as the sole oxidant to afford gamma-lactones has been developed. This catalyzed cyclization process has a broad substrate scope and affords gamma-lactones in good to excellent yields.
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