4.8 Article

Orthogonal Photocleavage of a Monochromophoric Linker

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 132, Issue 33, Pages 11431-11433

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja1047736

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Funding

  1. Grant Agency of the Czech Republic [203/09/0748]
  2. Ministry of Education, Youth and Sports of the Czech Republic [MSM0021622413]
  3. European Union (CETO-COEN) [CZ.1.05/2.1.00/01.0001]

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The 4-acetyl-2-nitrobenzyl moiety, substituted in both benzylic and phenacyl positions with leaving groups, has been proposed as a monochromophoric photocleavable linker. The attached groups can be disconnected selectively and orthogonally upon irradiation.

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