Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 132, Issue 19, Pages 6648-+Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja1009037
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Funding
- NIH/NIGMS [R01GM090270]
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A GPI anchor bearing unsaturated fatty acid lipid chains (1) was synthesized by a highly convergent strategy employing the para-methoxybenzyl group for permanent hydroxyl protection. The final global deprotection was achieved by an efficient three-step, one-pot procedure to give an 81% isolated yield of the target structure.
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