Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 132, Issue 16, Pages 5564-+Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja100585w
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Funding
- JSPS
- MEXT, Japan
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Short peptides were induced into a-helix conformations in water through enclathration to an artificial hydrophobic cavity. Peptides with two aromatic residues showed high affinity for the host, and these intermolecular aromatic-aromatic interactions specifically drove the helical folding of short peptides.
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