4.8 Article

A DNA Crystal Designed to Contain Two Molecules per Asymmetric Unit

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 132, Issue 44, Pages 15471-15473

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja104833t

Keywords

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Funding

  1. NIGMS, National Institute of Health [Y1 GM-0080-03]
  2. U.S. Department of Energy [DE-AC02-98CH10886]
  3. NIGMS [GM-29554]
  4. NSF [CTS-0608889, CCF-0726378]
  5. ARO, via Pegasus Corporation [W91 IFF-08-C-0057]
  6. ARO [MURI W91 INF-07-1-0439]
  7. ONR [N000140910181, N000140911118]
  8. W. M. Keck Foundation

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We describe the self-assembly of a DNA crystal that contains two tensegrity triangle molecules per asymmetric unit. We have used X-ray crystallography to determine its crystal structure. In addition, we have demonstrated control over the colors of the crystals by attaching either Cy3 dye (pink) or Cy5 dye (blue-green) to the components of the crystal, yielding crystals of corresponding colors. Attaching the pair of dyes to the pair of molecules yields a purple crystal.

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