Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 131, Issue 16, Pages 5738-+Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja900984x
Keywords
-
Categories
Funding
- 973 Program [2007CB210205]
- NNSFC [20602034, 20832004]
- NCET
Ask authors/readers for more resources
Pd-catalyzed decarboxylative cross-coupling of aryl iodides, bromides, and chlorides with potassium oxalate monoesters has been discovered. This reaction is potentially useful for laboratory-scale synthesis of aryl and alkenyl esters. Bulky, electron-rich bidentate phosphine ligands are preferred in the reaction, whereas Cu is not needed for decarboxylation. Theoretical calculations suggest a five-coordinate Pd(II) transition state for decarboxylation with an energy barrier of similar to 30 kcal/mol.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available