Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 131, Issue 17, Pages 6088-+Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja901876z
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Funding
- National Science Foundation [CHE-0518293]
- NIH/NIGMS for postdoctoral
- Agence Nationale pour la Recherche and the Region Aquitanic
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A new class of bead-based microarray that uses electrogenerated chemiluminescence (ECL) as a readout mechanism to detect multiple antigens simultaneously is presented. This platform demonstrates the possibility of performing highly multiplexed assays using ECL because all the individual sensing beads in the array are simultaneously imaged and individually resolved by ECL. Duplex and triplex assay results are demonstrated as well as a cross reactivity study.
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