Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 131, Issue 14, Pages 5024-+Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja8094075
Keywords
-
Categories
Funding
- Natural Sciences and Engineering Research Council of Canada (NSERC)
- Merck Frosst Center
Ask authors/readers for more resources
We report the first example of a coupling reaction of chiral secondary boronic esters generated by the hydroboration of vinyl arenes. In order for the reaction to take place in high yields, the use of silver oxide as a base and the presence of at least 8 equiv of triphenyl phosphine per Pd are required. The reaction proceeds with >90% retention of configuration in all cases except one. Remarkably, the linear boronate ester does not react under these conditions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available