4.8 Article

Norepinephrine: Material-Independent, Multifunctional Surface Modification Reagent

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 131, Issue 37, Pages 13224-13225

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja905183k

Keywords

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Funding

  1. National Research Foundation [R31-2008-000-10071-0]
  2. Ministry of Health Welfare [0920340]
  3. NIH [DE014193]
  4. Korea Health Promotion Institute [0920340] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
  5. Ministry of Education, Science & Technology (MoST), Republic of Korea [R31-2008-000-10071-0] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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A facile approach for material-independent surface modification using norepinephrine was investigated. pH-induced oxidative polymerization of norepinephrine forms adherent films on vastly different types of material: surfaces of noble metals, metal oxides, semiconductors, ceramics, shape-memory alloys, and synthetic polymers. Secondary biochemical functionalizations such as immobilization of proteins and growth of biodegradable polyester on the poly(norepinephrine) films were demonstrated.

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