Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 131, Issue 17, Pages 6052-+Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja809639c
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Funding
- Cosmetology Research Foundation
- Ministry of Education, Culture, Sports, Science. and Technology of Japan (MEXT)
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A collagen model peptide-attached dendrimer was synthesized as a potential functional Collagen material. The peptides that clustered at the surface of the dendrimer formed a thermally reversible collagen-like triple helix. This dendrimer worked as a drug carrier with thermosensitive release capabilities, although it did not exhibit a tower critical solution temperature. From this dendrimer, the hydrogel could be made at low temperature.
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