4.8 Article

Cross-Coupling of Alkenyl/Aryl Carboxylates with Grignard Reagent via Fe-Catalyzed C-O Bond Activation

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 131, Issue 41, Pages 14656-+

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja907281f

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Funding

  1. Peking University
  2. National Sciences of Foundation of China [20672006, 20821002]
  3. National Basic Research Program of China [2009CB825300]

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Iron-catalyzed cross-coupling of alkenyl/aryl carboxylates with primary alkyl Grignard reagent was described. This reaction brought a new family of electrophiles to iron catalysis. The combination of an inexpensive carboxylate electrophile and an iron catalyst would generate ample advantages.

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