Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 131, Issue 5, Pages 1628-+Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja808772z
Keywords
-
Categories
Funding
- NNSFC [50425310, 20874092, 20534020, 20674079]
Ask authors/readers for more resources
We report a novel strategy for the high-efficiency preparation of macrocyclic diblock copolymers at relatively high concentrations via the combination of supramolecular self-assembly and selective click reactions, relying on the fine control of spatial accessibility between terminal reactive groups. The linear precursor, alpha-alkynyl-omega-azido heterodifunctional poly(2-(2-methoxyethoxy)ethyl methacrylate)-b-poly(oligo(ethylene glycol) methyl ether methacrylate), linear-PMEO(2)MA-b-POEGMA-N-3, self-assembles into micelles with PMEO(2)MA cores and POEGMA coronas at elevated temperatures. The spatial separation between reactive alkynyl and azide groups precludes click reactions within micelle entities. On the other hand, due to the unimer-micelle exchange equilibrium and the fact that unimer concentration is typically tow (critical micellization concentration, CMC), click reactions occur exclusively for unimers. This eventually led to complete intramolecular cyclization of all linear precursors.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available