Multiresponsive Supramolecular Nanogated Ensembles

A new multiresponsive supramolecular nanogated ensemble has been developed by introducing B-cyclodextrin (B-CD) into polymer-grafted mesoporous silica. The crosslinked polymer produced by host-guest interaction between B-CD and diazo-linker works as a gatekeeper to control the release of trapped molecules from hybrid materials. The presence of UV light, a-CD, or disulfide reducing agent can effectively open the polymeric network and release the loading with different dynamics.