4.8 Article

Rhenium-Catalyzed Regioselective Alkylation of Phenols

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 131, Issue 29, Pages 9914-+

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja904360k

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Funding

  1. Ministry of Education, Culture, Sports, Science, and Technology of Japan

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Treatment of phenol derivatives with terminal alkenes in the presence of a catalytic amount of a rhenium complex, Re-2(CO)(10), gave monoalkylated phenol derivatives in good to excellent yields. This reaction proceeds at the ortho- or para-position of phenols regioselectively.

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