4.8 Article

A Temperature-Sensitive Liposomal 1H CEST and 19F Contrast Agent for MR Image-Guided Drug Delivery

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 131, Issue 4, Pages 1380-+

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja8087532

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Funding

  1. EU [FP6-2004-NMP-NI-4/IP 026668-2]

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A novel temperature-sensitive liposomal. MRI contrast agent has been developed, which allows drug carrier localization using H-1 CEST with simultaneous quantification of the drug release using F-19 MR imaging in response to a local temperature increase.

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