4.8 Article

Catalytic Enantioselective Meerwein-Eschenmoser Claisen Rearrangement: Asymmetric Synthesis of Allyl Oxindoles

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 130, Issue 48, Pages 16162-+

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja807026z

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Funding

  1. NSF [CRE-0616885]

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The first catalytic, enantioselective Meerwein-Eschenmoser Claisen rearrangement has been achieved, Palladium(II) BINAP or phosphinooxazoline catalysts were employed to generate oxindole products with 100% conversion and up to 92% ee.

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