4.8 Article

Rhodium-Catalyzed Transannulation of 1,2,3-Triazoles with Nitriles

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 130, Issue 45, Pages 14972-+

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja805079v

Keywords

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Funding

  1. National Institutes of Health [GM-64444, DA-19372]
  2. Skaggs Institute for Chemical Biology
  3. Pfizer, Inc.

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Stable and readily available 1-sulfonyl triazoles are converted to the corresponding imidazoles in good to excellent yields via a rhodium(II)-catalyzed reaction with nitriles. Rhodium iminocarbenoids are proposed intermediates.

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