Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 130, Issue 17, Pages 5608-+Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja800345r
Keywords
-
Categories
Funding
- NCRR NIH HHS [S10 RR013866] Funding Source: Medline
Ask authors/readers for more resources
Enantioselective organocatalytic Michael addition of aldehydes to nitroethylene catalyzed by (S)diphenylprolinol silyl ether provides beta-substituted-delta-nitroalcohols in nearly optically pure form (96-99% ee). The Michael adducts bear a single substituent adjacent to the carbonyl and can be efficiently converted to protected Y(2-)amino acids, which are essential for the systematic conformational studies of Y-peptide foldamers.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available