Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 130, Issue 52, Pages 17648-+Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja807099s
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Funding
- NIH [R01-CA115296, R01-EB-005905, S10-RR-023010]
- Lewis Family Fund
- Ellison Foundation
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Efficient chemical synthesis of a trifunctional, hydroxyapatite-binding molecule, which provides simultaneous in vivo imaging by NIR fluorescence and SPECT/CT has been described. Quantitation by SPECT provides the gold standard by which NIR fluorescence tomography of breast cancer microcalcifications can now be compared and optimized.
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