Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 130, Issue 37, Pages 12248-+Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja804838y
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- Wyeth and Rutgers
- The State University of New Jersey
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Highly enantioselective organocatalytic aldol additions of aisothiocyanato imides to aldehydes are reported. These reactions provide convenient access to enantiomerically enriched and protected beta-hydroxy-a-amino acids with catalyst loadings as low as 1 mol%.
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