4.8 Article

Signal amplification via intramolecular energy transfer using tripodal neutral iridium(III) complexes upon binding to avidin

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 130, Issue 12, Pages 3726-+

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja710803p

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Funding

  1. National Research Foundation of Korea [과06A1501] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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A neutral tripod system for biotin-avidin assays, which is composed of biotin, Flrpic as an energy acceptor, and mCP as an energy donor, offers remarkable sensitivity over traditional transition metal based protein probes due to the intramolecular energy transfer and increased hydrophobicity associated with the avidin binding site and neutral probe 1.

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